Can we use other Adafruit Feather with the same pinouts for the main microcontroller beside nRF52840 Sense ? For example will these board be compatible? Adafruit Feather 32u4 Bluefruit LE, Adafruit Feather M0 Bluefruit LE, or the Feather ESPs? If not is that a hardware/software constrain?
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It should be compatible with the Feather 840 Express. As for the boards above mentioned, I have not tested it with them, but in general it will not be 100% compatible with other Feather boards due to both hardware and software differences. In terms of hardware, even though the pinout appears to be the same across all the feather boards, there are several differences. Some of them being number and locations of PWM pins, Analog pins, battery voltage sensor pin, etc. In the case of FlowIO, all the pneumatic parts need to be connected to PWM pins.
If one of these microcontrollers has the same locations of the PWM, Analog, and Battery pins as the current microcontroller, then there is a good chance it would be hardware-compatible.